n-Octyl-β-D-thioglucopyranoside

Ref. 3D-O-2710

Product Information

• Name: n-Octyl-β-D-thioglucopyranoside
• Synonyms: Octyl-beta-D-thioglucoside
• Brand: Biosynth
• Description: Octyl-beta-D-thioglucopyranoside is an alkylglycoside non-ionic detergent used for cell lysis and membrane protein isolation. As it is uncharged, it is unlikely to cause protein denaturation or refolding issues, allowing for the isolation of intact macromolecular complexes without affecting protein-protein interactions. Octyl-beta-D-thioglucopyranoside is also known as n-Octyl-beta-D-thioglucoside or OTG and has an aggregation number of 189. It is dialyzable from membrane protein preparations and has a Critical Micelle Concentration (CMC) of 9mM. Octyl-beta-D-thioglucopyranoside has similar uses and properties to that of another frequently used surfactant, n-Octyl-beta-D-glucopyranoside. However, Octyl-beta-D-thioglucopyranoside is more stable and is unaffected by beta-glucosidase enzyme due to its thioether linkage.

Chemical properties

• Molecular weight: 308.44 g/mol
• Formula: C₁₄H₂₈O₅S