β-Aescin

CAS: 11072-93-8

Ref. 3D-OA10870

Product Information

• Name: β-Aescin
• Synonyms: b-Escin, (2S,3S,4S,5R,6R)-6-[[(3S,4S,6aR,6bS,8R,8aR,9R,10R,14bR)-9-acetoxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy]tetrahydropyran-2-carboxylic acid, (5ξ,8ξ,9ξ,10ξ,16α,17ξ,18ξ,22α)-22-(acetyloxy)-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl α-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid, Flogencyl, beta-Aescin, beta-Aescinu, beta-Aescinu [Czech], beta-Aescusan, beta-Escin, beta-Reparil

Description

b-Aescin is a member of the escin family, a mixture of triterpenes. It can be isolated from horse chestnut trees and has been used medicinally for centuries. b-Aescin has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis and is used in traditional medicine to treat pain, inflammation, and edema. b-Aescin also inhibits apoptosis in HL60 cells, neuronal death in mice, and cytosolic Ca2+ levels. This drug also has inhibitory properties against a wide range of cell types by binding to nuclear DNA. However, it does not bind to mitochondrial DNA or the ryanodine receptor.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,131.26 g/mol
• Formula: C₅₅H₈₆O₂₄
• Purity: Min. 95%
• Color/Form: White To Off-White Solid