Aminosidine
CAS:
Ref. 3D-OA11590
Product Information
Name:Aminosidine
Synonyms:
- Paromomycin
Brand:Biosynth
Description:Aminosidine is a nucleoside analogue that inhibits the HIV-1 reverse transcriptase and the integrase, which are enzymes involved in viral DNA synthesis. Aminosidine is active against Leishmania spp., but not against bacteria. Aminosidine has been shown to be effective in experimental models of human bowel disease and in patients with inflammatory bowel disease. It was also found to be active against wild-type strains of human immunodeficiency virus type 1, but not resistant mutants. The mechanism of action is the inhibition of cellular mitochondrial membrane potential.
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Chemical properties
Purity:Min. 95%