Fleetamine
Ref. 3D-OF63532
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Product Information
- 3-O-a-D-Glucopyranosyl-swainsonine
Fleetamine is a piperidine compound that has been shown to be an inhibitor of the enzyme glycosylation. Inhibitors of glycosylation are useful for treating diseases such as diabetes and Alzheimer's disease. It is thought that Fleetamine may inhibit human glycosylating enzymes, such as glucosyl transferase, which catalyzes the addition of a glucose molecule to a protein. This inhibition prevents the formation of oligosaccharides and glycoconjugates, which are necessary for proper functioning of cells.
Fleetamine is also capable of inhibiting lactam formation in humans by binding to the active site on the enzyme ligand. The ligand is responsible for connecting two amino acids in order to form a peptide bond. The inhibition of this process will prevent the synthesis of proteins and enzymes necessary for cellular function.
Fleetamine has been shown to have potential as an inhibitor against rationalized inhibitors, which are compounds that bind at sites other than
Chemical properties
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