GD1a-Ganglioside sodium
CAS: 12707-58-3
Ref. 3D-OG03917
| 1mg | 325.00 € | ||
| 2mg | 452.00 € | ||
| 5mg | 947.00 € | ||
| 10mg | 1,702.00 € | ||
| 25mg | 3,646.00 € |
Product Information
- GD1a-Ganglioside
- G<sub>D1a</sub>
- GD1a
- Ganglioside B1
- Ganglioside B<sub>1</sub>
- Ganglioside G3
- Ganglioside G<sub>3</sub>
- Ganglioside G<sub>D1a</sub>
- Ganglioside G<sub>II</sub>
- Ganglioside GD1a
- See more synonyms
- Ganglioside GII
- disialoganglioside-gd1A from bovine*brain
GD1a (shown as sodium salt) is one of the major gangliosides in neuronal and glial membranes. It has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. It plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. GD1a ganglioside also interacts with botulinum neurotoxin and is crucial for its entry into cells (Kolter, 2012).
Chemical properties
Technical inquiry about: 3D-OG03917 GD1a-Ganglioside sodium
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