GD3-Ganglioside sodium
CAS: 62010-37-1
Ref. 3D-OG03922
1mg | 583.00 € | ||
2mg | 1,038.00 € | ||
5mg | 2,314.00 € | ||
10mg | 4,461.00 € |
Product Information
- Disialosyllactosylceramide
- G(D3) Ganglioside
- G<sub>D3</sub>
- GD3
- GD3 Ganglioside
- Ganglioside D3
- Ganglioside D<sub>3</sub>
- Ganglioside G<sub>D3</sub>
- Ganglioside, GD3
- Gd(3)
- See more synonyms
- N-Acetylneuraminyl N-acetylneuraminylgalactosylglucosylceramide
- Disialohematoside
GD3 (shown as sodium salt) has a core disaccharide structure (Galβ1,4Glc) with two sialic acids linked α2,3/α2,8 to the non-reducing galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD3 is a minor ganglioside in most normal tissues but plays a crucial role in the development of the brain; it is significantly reduced in adults. However, expression of GD3 is increased in pathological conditions, such as, cancers and neurodegenerative disorders (Malisan, 2002). GD3 was the first cancer-associated ganglioside discovered that promotes adhesion and invasion of cancers. GD3 and GD2 are highly expressed in a various malignant tumours and have become potential targets for next-generation cancer therapy (Liu, 2018).
Chemical properties
Technical inquiry about: 3D-OG03922 GD3-Ganglioside sodium
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