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GD2-Ganglioside
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GD2-Ganglioside

CAS: 65988-71-8

Ref. 3D-OG06830

1mg
3,160.00 €
50µg
723.00 €
100µg
1,017.00 €
200µg
1,541.00 €
500µg
2,592.00 €
Estimated delivery in United States, on Tuesday 3 Dec 2024

Product Information

Name:
GD2-Ganglioside
Synonyms:
  • Disialoganglioside-GD2
  • 65988-71-8
  • Disialoganglioside GD<sub>2</sub>
  • G<sub>D2</sub>
  • Ganglioside G<sub>D2</sub>
Description:

GD2 (shown as sodium salt) has a core trisaccharide structure (GalNAc-b-1,4-Gal-b-1,4-Glc) with its two sialic acids linked b-2,3/b-2,8 to the inner galactose residue and ceramide linked to position 1 on the reducing terminal glucose residue. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,675.94 g/mol
Formula:
C78H138N4O34·xNa
Purity:
Min. 95 Area-%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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