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GQ1b-Ganglioside ammonium
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GQ1b-Ganglioside ammonium

CAS: 68652-37-9

Ref. 3D-OG175969

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Estimated delivery in United States, on Thursday 2 Jan 2025

Product Information

Name:
GQ1b-Ganglioside ammonium
Synonyms:
  • GQ1b Ganglioside
  • Ganglioside GQ1B
Description:

GQ1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, two sialic acids (NeuAc) linked α2,3/α2,8 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Anti-GQ1b ganglioside antibody is associated with Miller Fisher syndrome and is also found in patients with related conditions that may share the same pathogenic mechanism, such as, Bickerstaff brainstem encephalitis. Thus, the measurement of anti-GQ1b antibody in suspected cases of Miller Fisher syndrome is a useful diagnostic marker (Paparounas, 2004). It has been found that GQ1b ganglioside contributes to synaptic transmissions and synapse formation. Low concentrations of GQ1b ganglioside, evoked dopamine (DA) release from laboratory tissues (Chen, 2018).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Formula:
C106H182N6O56·xNH4
Purity:
Min. 95%
MDL:
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Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
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P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
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