Gangliotriose
CAS: 1355005-58-1
Ref. 3D-OG29094
| 1mg | 400.00 € | ||
| 2mg | 569.00 € | ||
| 5mg | 881.00 € | ||
| 10mg | 1,276.00 € | ||
| 25mg | 2,296.00 € |
Product Information
- Asialo-GM2-trisaccharide
Gangliotriose is the core trisaccharide structure in gangliosides, such as, GD2 (GalNAcβ1,4Galβ1,4Glc) (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that posess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).
Chemical properties
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