N-Glycolyl GM1 ganglioside
Ref. 3D-OG63297
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire |
Product Information
- Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)CersGM1 NeuGc-Ganglioside
N-Glycolyl GM1 ganglioside has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with N-glycolyl sialic acid linked α2,3 to the central galactose residu,e and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). SV40, Py, and the human BK viruses are unusual among viruses in that they use glycolipids as their major cell surface receptors. SV40 uses the N-glycolylneuraminic acid (NeuGc) analog of the ganglioside GM1 [GM1(Gc)] as the cell surface receptor and it gave markedly stronger binding signals than the NeuAc analog [GM1(Ac)] (Campanero-Rhodes, 2007).
Chemical properties
Technical inquiry about: 3D-OG63297 N-Glycolyl GM1 ganglioside
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