Leu-Gly • ½ H2O

CAS: 686-50-0

Ref. 3D-OLG-3024

Product Information

• Name: Leu-Gly • ½ H2O
• Synonyms: L-Leucyl-Glycine, (S)-2-(2-Amino-4-methylpentamido)acetic acid, 101: PN: EP2161028 PAGE: 10 claimed protein, 10: PN: WO2011159938 SEQID: 76 claimed protein, 1374: PN: EP2071334 SEQID: 1452 claimed protein, 1374: PN: WO2009077864 SEQID: 1452 claimed protein, 147: PN: US20130123467 SEQID: 176 claimed protein, 2-[(2S)-2-Amino-4-methylpentanamido]acetic acid, 2-[[(2S)-2-Amino-4-methylpentanoyl]amino]acetic acid, 202: PN: WO2011032181 SEQID: 222 unclaimed protein, 210: PN: WO2009114815 SEQID: 222 unclaimed protein, 35: PN: WO0028996 SEQID: 4 unclaimed protein, 436: PN: WO2005081628 SEQID: 438 claimed protein, <span class="text-smallcaps">L</span>-Leucylglycine, Glycine, <span class="text-smallcaps">L</span>-leucyl-, Glycine, N-<span class="text-smallcaps">L</span>-leucyl-, H-Leu-Gly-OH, L-Leucyl-glycine, Leu-Gly hydrate, Morphine tolerance peptide

Description

Leu-Gly is a cyclic peptide that is composed of the amino acid sequence Leu-Gly. It has antimicrobial, anti-inflammatory, and immunomodulatory properties. This peptide exhibits calcium binding, which may be due to its structural analysis with trifluoroacetic acid in human serum. A model system using coli K-12 cells was used to study the biological properties of Leu-Gly. The locomotor activity of these cells was inhibited by Leu-Gly, which may be due to its ability to bind with cyclic adenosine monophosphate (cAMP) receptors on the cell surface.
LEU Gly is a member of the class of antimicrobial peptides that are important for fighting infections. It has been shown to have strong activity against E. coli K12 and various strains of Staphylococcus aureus isolated from humans with autoimmune diseases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 197.23 g/mol
• Formula: C₈H₁₆N₂O₃H₂O
• Purity: Min. 95%