GT1b-Oligosaccharide

CAS: 75663-36-4

Ref. 3D-OO16323

Product Information

• Name: GT1b-Oligosaccharide
• Brand: Biosynth
• Description: GT1b oligosaccharide (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, and sialic acid (NeuAc) linked α2,3 to the terminal galactose residue (Ledeen, 2009). The GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes; it interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus and others (Low, 2006).

Chemical properties

• Molecular weight: 1,581.39 g/mol
• Formula: C₅₉H₉₆N₄O₄₅
• Purity: (%) Min. 98%
• Color/Form: Powder