GT1a-Oligosaccharide
Ref. 3D-OO46224
| 1mg | 526.00 € | ||
| 2mg | 783.00 € | ||
| 5mg | 1,435.00 € | ||
| 10mg | 2,210.00 € | ||
| 25mg | 5,082.00 € |
Product Information
- Neu5Aca2-8Neu5Aca2-3Galb1-3GalNAcb1-4 (Neu5Aca2-3)Galb1-4Glc
GT1a oligosaccharide has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid (NeuAc) linked α2,3 to the inner galactose residue and two sialic acids (NeuAc) linked α2,3/α2,8 to the terminal galactose residue (Ledeen 2009). GuillainâBarré syndromes, a major cause of acute autoimmune neuromuscular paralysis, is linked to C. jejuni and several gangliosides. Anti-ganglioside antibodies are associated with specific clinical subtypes of GuillainâBarré syndromes, including: anti-GD1a antibodies with AMAN56 and anti-GQ1b; and anti-GT1a antibodies with acute oropharyngeal palsy (Goodfellow, 2016).
Chemical properties
Technical inquiry about: 3D-OO46224 GT1a-Oligosaccharide
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