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GD1b-Oligosaccharide
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GD1b-Oligosaccharide

Ref. 3D-OO46227

1mg
861.00 €
2mg
1,426.00 €
5mg
2,188.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
GD1b-Oligosaccharide
Synonyms:
  • Galb1-3GalNAcb1-4(Neu5Aca2-8Neu5Aca2-3)Galb1-4Glc
Description:

GD1b oligosaccharide (shown as ammonium salt) is the carbohydrate moiety in one of the major gangliosides in neuronal and glial membranes; it has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with its two sialic acids linked α2,3/α2,8 to the inner galactose residue (Ledeen, 2009). GD1b ganglioside acts as a receptor for BK virus as well as for heat-labile LTII-a toxin, produced by enteropathogenic E. coli. GD1b ganglioside also interacts with tetanus neurotoxin (TeNT) and is crucial for its entry into cells (Kolter, 2012). The functional significance of ammonia in the brain is not yet fully understood. However, NH4 + stimulates Na+, K+ activated ATPase causing stabilization of the neuronal membranes of which gangliosides are major structural components. Further, ammonia is known to inhibit lysosomal enzymes which include enzymes degrading gangliosides (Modi, 1994).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,334.1 g/mol
Formula:
C48H77N3O37Na2
Purity:
Min. 90%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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