GT3-Oligosaccharide

Ref. 3D-OO46229

Product Information

• Name: GT3-Oligosaccharide
• Synonyms: Neu5Aca2-8Neu5Aca2-8Neu5Aca2-3Galb1-4Glc
• Brand: Biosynth
• Description: GT3 oligosaccharide (free acid) is a disaccharide (Galβ1,4Glc) with three sialic acid residues (NeuAc) linked α2,8/α2,8/α2,3 to the galactose residue (Ledeen, 2009). The GT3 ganglioside is the carbohydrate moiety in the GT3 ganglioside, which is implicated in type 1 diabetes. GT3 ganglioside is expressed on pancreatic cells and is the target antigen of anti-GM3-antibodies, which contribute to the autoimmune destruction of pancreatic beta cells (Misasi, 1997). GT3 ganglioside is also abundant in lung tissues and the nervous system.

Chemical properties

• Molecular weight: 1,282.01 g/mol
• Formula: C₄₅H₇₀N₃O₃₅Na₃
• Purity: Min. 90%
• Color/Form: Powder