GM1a-Oligosaccharide
Ref. 3D-OO46231
| 1mg | 436.00 € | ||
| 2mg | 647.00 € | ||
| 5mg | 986.00 € | ||
| 10mg | 1,392.00 € | ||
| 25mg | 2,551.00 € |
Product Information
- Galb1-3GalNAcb1-4(Neu5Aca2-3)Galb1-4Glc
GM1a pentasaccharide (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue (Ledeen, 2009). GM1a pentasaccharide is the carbohydrate moiety in GM1a ganglioside which interacts and modulates tyrosine kinases, such as, neural tropomyosin receptor kinase A (TrkA), by inducing the release of neurotrophins from fibroblast cells and the epidermal growth factor receptor (EGFR) (Higuero, 2009). Oligosaccharide domain of monosialylated glycosphingolipid GM1 of a-series that specifically interacts with cholera toxin B subunit (CBT) fromâ¯V. cholerae, heat-labile toxin B subunit (LTB) fromâ¯E. coliâ¯and alpha toxin fromâ¯C. perfrigens. This ganglioside is abundant in nervous system as well as in other peripheral tissues (Chiricozzi, 2020).
Chemical properties
Technical inquiry about: 3D-OO46231 GM1a-Oligosaccharide
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