GT2-Oligosaccharide

Ref. 3D-OO46234

Product Information

• Name: GT2-Oligosaccharide
• Synonyms: GalNAcb1-4(Neu5Aca2-8Neu5Aca2-8Neu5Aca2-3)Galb1-4Glc
• Brand: Biosynth
• Description: GT2 oligosaccharide (free acid) has a core trisaccharide structure (GalNAcβ1,4Galβ1,4Glc) with three sialic acid residues (NeuAc) linked α2,8/α2,8/α2,3 to the inner galactose residue (Ledeen, 2009). GT2 oligosaccharide is the carbohydrate moiety in the GT2 ganglioside. A key role has been reported for gangliosides, such as, GT1b and GT2 as modulators in the interaction between microglia (resident cells of the brain that regulate brain development) and brain tumors. It is possible that they will be important targets for therapeutical intervention in the near future (Daniele, 2020). In addition, C-series gangliosides, such as GT3, GT2, GQ1c, and CP1c are expressed in normal pancreatic tissue but are practically lost in the pancreas of diabetic animals (Saito, 1999).

Chemical properties

• Molecular weight: 1,485.2 g/mol
• Formula: C₅₃H₈₃N₄O₄₀Na₃
• Purity: Min. 95%