Product Information
- Bridion6A,6B,6C,6D,6E,6F,6G,6H-Octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-gamma-cyclodextrin
- 6A,6B,6C,6D,6E,6F,6G,6H-Octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-cyclodextrin
- Sugammadex acid
- Bridion
- γ-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-
Sugammadex is a modified gamma-cyclodextrin specifically designed to reverse the effects of steroidal non-depolarizing neuromuscular blocking drugs, particularly rocuronium and vecuronium. In anesthesiology, it offers a novel approach to neuromuscular blockade reversal by directly encapsulating and inactivating these muscle relaxants. Sugammadex forms tight 1:1 complexes with free plasma rocuronium or vecuronium molecules, rapidly reducing their concentration at the neuromuscular junction. This mechanism allows for fast and predictable reversal of neuromuscular blockade, even from deep levels, without the need for anticholinesterases or antimuscarinic agents. Sugammadex has also shown promise in special populations, including pregnancy, pediatrics, and patients with renal or hepatic impairment.
Chemical properties
Technical inquiry about: 3D-OS165431 Sugammadex
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