1-(6-Chloropyridazin-3-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one
CAS:
Ref. 3D-PAA24687
1g
1,013.00€
100mg
377.00€
Product Information
Name:1-(6-Chloropyridazin-3-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one
Brand:Biosynth
Description:1-(6-Chloropyridazin-3-yl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one (1) was found to be a potent inhibitor of β amyloid fibril formation and a lead compound for the treatment of Alzheimer's disease. The compound inhibits amyloid fibril formation by binding to the hydrophobic region in the core of the fibrils and preventing crosslinking. 1 also inhibits pancreatic β cell secretion, resulting in reduced production of insulin, which causes glucose intolerance. This drug has been shown to reduce glycemic levels in diabetic mice without causing hypoglycemia.
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Chemical properties
Molecular weight:210.62 g/mol
Formula:C8H7ClN4O
Purity:Min. 95%
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