[Sar1,Thr8]-Angiotensin II

CAS: 53632-49-8

Ref. 3D-PAN-4102-V

Product Information

• Name: [Sar1,Thr8]-Angiotensin II
• Synonyms: Sar-Arg-Val-Tyr-Ile-His-Pro-Thr, AngiotensinII, 1-(N-methylglycine)-5-L-isoleucine-8-L-threonine-, 159: PN: WO02064734SEQID: 159 claimed protein, Sarthran, [Sar1,Ile5,Thr8]-angiotensin II, L-Threonine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, Sar-Arg-Val-Tyr-Ile-His-Pro-Thr-OH
• CAS: 53632-49-8

Description

Angiotensin II is a peptide that is produced in the body and has a variety of effects. It is an activator of angiotensin receptors, which are found on cells throughout the body. Angiotensin II also binds to ligand binding sites on the surface of cells, which are called receptors. The receptor-ligand complex activates or inhibits ion channels in the cell membrane, which results in changes in cell function.

Angiotensin II has been shown to inhibit the function of potassium channels and voltage-gated calcium channels. It also induces release of nitric oxide from endothelial cells and activates protein kinase C, leading to cellular responses such as increased blood pressure and vasoconstriction. This peptide can be used as a research tool for studying ion channels, cell biology, pharmacology, and life science.

• Brand: Biosynth

Chemical properties

• Molecular weight: 956.1 g/mol
• Formula: C₄₄H₆₉N₁₃O₁₁
• Purity: Min. 95%