H-Gly-Tyr-Pro-Gly-Gln-Val-NH2

Ref. 3D-PAR-3673-PI

Product Information

• Name: H-Gly-Tyr-Pro-Gly-Gln-Val-NH2
• Synonyms: H-Gly-Tyr-Pro-Gly-Gln-Val-Amide, GYPGQV-Amide
• Brand: Biosynth
• Description: H-Gly-Tyr-Pro-Gly-Gln-Val-NH2 is a peptide that belongs to the PAR4 family of protease-activated receptors. PAR4 is a G protein coupled receptor, which activates intracellular signaling pathways and has been identified as an important regulator of cardiovascular function. This peptide binds to PAR4 and stimulates the production of cAMP in human platelets. It also has an effect on the coagulation cascade by inhibiting thrombin formation, suggesting that it may be useful for treating hypertension or coagulopathies.PAR4 is expressed in various tissues including heart, kidney, lung, liver, pancreas and brain. The expression pattern varies with age and sex.

Chemical properties

• Molecular weight: 618.7 g/mol
• Formula: C₂₈H₄₂N₈O₈
• Purity: Min. 95%