N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite
CAS: 110782-31-5
Ref. 3D-PB08471
1g | 161.00 € | ||
2g | 222.00 € | ||
5g | 462.00 € | ||
10g | 728.00 € | ||
25g | 1,261.00 € |
Product Information
- N6-Benzoyl-5'-O-DMT-2'-O-methyl-D-adenosine 3'-CE phosphoramidite
- Ac-dA Phosphoramidite
- 2'-OMe-Bz-A Phosphoramidite
- 2'-O-Methyl-Ra(N-Bz)Phosphoramidite
- 2'-O-Methyl-N6-Benzoyl-5'-O-DMT-Adenosine-3'-CE-Phosphoramidite
N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block in the chemical synthesis of oligonucleotides containing a 2’-O-methyl adenosine nucleoside unit. The use of a chemical synthesis rather than an enzymatic one allows oligonucleotides of a desired sequence to be produced. 3’-Cyanoethyl phosphoramidites are typically used by substitution of the di-isopropylamine group with an appropriate alcohol in the presence of an azole catalyst. Oligonucleotides containing 2'-O-methylribonucleoside units have shown site-specific cleavage with E. coli RNase H, either at a hairpin loop or at a stem region.
Chemical properties
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