Chloro-AlaOiPr-amidite

Ref. 3D-PC46547

Product Information

• Name: Chloro-AlaOiPr-amidite
• Brand: Biosynth
• Description: Chloro-AlaOiPr-amidite is an anticancer drug that is a modified form of the nucleoside 2'-deoxyadenosine. It has been shown to be active against both DNA and RNA tumor cells in vitro. Chloro-AlaOiPr-amidite was also found to be effective against HIV-1 when tested in vivo, showing antiviral activity. The drug is synthesized by reacting an acid chloride with the amine group of AlaOiPr. In this reaction, the chloride ion attacks the amine group, displacing a proton from the nitrogen atom and forming a chloroamine species. The chloramine then reacts with the nucleoside to give rise to an intermediate called chloro-AlaOiPr-amidite which can then be reacted with a phosphoramidite or ribonucleotide to yield chloro-AlaOiPr-phosphoramidite

Chemical properties

• Purity: Min. 95%