Product Information
- 1,2,3-Triazine, 5-Bromo-
Etoricoxib is a nonsteroidal anti-inflammatory drug that is marketed for the relief of osteoarthritis and rheumatoid arthritis. Etoricoxib is an inhibitor of cyclooxygenase-2, which is involved in the inflammatory response. It also inhibits the activity of lipoxygenases, which are enzymes that oxidize fatty acids to form leukotrienes. Etoricoxib has been found to be a potent inhibitor of cytochrome P450 (CYP) 2C9, CYP2C19, CYP2D6 and CYP3A4. Etoricoxib was also found to bind to DNA in calf thymus tissue with high affinity. This binding may inhibit transcription or replication.
Chemical properties
Technical inquiry about: 3D-PEA07888 5-Bromo-1,2,3-triazine
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