![Suc-[Glu9,Ala11,15]-Endothelin-1 (8-21)](https://static.cymitquimica.com/products/3D/img/PED-4285-V.png "Click to enlarge")
Product Information
- IRL 1620 Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp (Suc: Succinyl)
- 28:PN: WO2007112069 SEQID: 19 claimed protein
- Irl 1620
Suc-[Glu9,Ala11,15]-Endothelin-1 (8-21) is a peptide that has been used as a research tool in pharmacology and protein interactions. Suc-[Glu9,Ala11,15]-Endothelin-1 (8-21) has been shown to be an agonist of the endothelin receptor. Endothelin-1 is a peptide that acts as a vasoconstrictor and plays an important role in the regulation of blood pressure.
Endothelin-1 is also an endogenous ligand for two G protein-coupled receptors, ETA and ETB. Interesting Endothelin-1 is the most abundant isoform and is expressed in endothelial cells of every blood vessel. It exerts its vasoconstrictor effects through binding to ETA receptors located on the smooth muscle.
Chemical properties
Technical inquiry about: 3D-PED-4285-V Suc-[Glu9,Ala11,15]-Endothelin-1 (8-21)
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