Product Information
- H-Tyr-Gly-Gly-Phe-Met(O)-OH
- L-tyrosylglycylglycyl-N-[(1S)-1-carboxy-3-(methylsulfinyl)propyl]-L-phenylalaninamide
Enkephalins are a group of endogenous peptides that are the most potent natural analgesic and have been shown to relieve pain by inhibiting neurotransmitters. The (Met(O)5)-enkephalin analog is a structural analog of the enkephalin peptide with a sulfoxide linkage at position 5. This analog has been shown to inhibit acetylcholine release from intestinal ganglia, which may be related to its effects on postsynaptic potentials and glutamate release. This compound also absorbs in the small intestine, where it is taken into the blood stream and transported to the brain. The (Met(O)5)-enkephalin analog has been shown to reduce pain in Sprague-Dawley rats, as well as inhibit intestinal transit time and stimulate intestinal motility.
Chemical properties
Technical inquiry about: 3D-PEK-3807-PI (Met(O)5)-Enkephalin
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