![[D-Ala2,D-Leu5]-Enkephalin](https://static.cymitquimica.com/products/3D/img/PEK-4115.png "Click to enlarge")
Product Information
- Tyr-D-Ala-Gly-Phe-D-Leu • AcOH • H2O
Enkephalins are endogenous opioid peptides that inhibit pain and have a variety of other physiological effects. They bind to specific receptors on the surface of neurons, which are called opioid receptors. Enkephalin is a peptide consisting of two amino acids, D-Ala2,D-Leu5. Enkephalins can be produced by linking two amino acids together with an amide bond or by modifying one of the amino acids in the sequence. This drug has been shown to induce mitochondrial membrane depolarization in hippocampal cells and autophagy in neuronal cells. It also has antinociceptive properties and is able to penetrate the blood-brain barrier due to its absorption enhancer property. The drug is also able to induce locomotor activity in mice and cause neuronal death in vivo models.
Chemical properties
Technical inquiry about: 3D-PEK-4115 [D-Ala2,D-Leu5]-Enkephalin
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