[D-Ala2,Met5]-Enkephalinamide

CAS: 100929-50-8

Ref. 3D-PEK-4117

Product Information

• Name: [D-Ala2,Met5]-Enkephalinamide
• Synonyms: Tyr-D-Ala-Gly-Phe-Met-NH2 • AcOH • H2O
• Brand: Biosynth
• Description: D-Ala2,Met5]-Enkephalinamide is a potent endogenous opioid peptide that binds to opioid receptors and has been shown to have both antinociceptive and depressant effects. It has been shown to be effective in a model system of pain, acting on the descending antinociceptive pathway from the rostral ventromedial medulla (RVM) to the spinal cord. D-Ala2,Met5]-Enkephalinamide has also been observed to inhibit locomotor activity in CD1 mice at sub-effective doses. D-Ala2,Met5]-Enkephalinamide has been shown to act through activation of both G protein-coupled mu opioids receptors and G protein-coupled delta opioid receptors.

Chemical properties

• Molecular weight: 664.77 g/mol
• Formula: C₂₈H₃₈N₆O₆S•CH₃COOH•H₂O
• Purity: Min. 95%