3-Chloroquinolin-8-amine
CAS: 139399-66-9
Ref. 3D-PFA39966
1g | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued | ||
2500mg | Discontinued |
Product Information
The synthesis of 3-chloroquinolin-8-amine is a two-step process. The first step requires the condensation of 3,4-dichloroaniline with nitromethane in the presence of a base to produce 3-(3,4-dichlorophenyl)-1,2,4-triazolone. This intermediate is then cyclized by treatment with an acid to produce 4-chloroquinoline. In the second step, treatment of 4-chloroquinoline with hydrochloric acid produces 3-(3,4-dichlorophenyl)quinoline.