Product Information
3,4,5-Trichloropicolinonitrile is a pyridine derivative that has been shown to be a potent inhibitor of the enzyme xanthine oxidase. Xanthine oxidase catalyses the oxidation of hypoxanthine to xanthine and then to uric acid. This reaction is important in the purification of nucleotides and in the production of uric acid as a component of urine. 3,4,5-Trichloropicolinonitrile binds reversibly to xanthine oxidase by means of its hydrazone group. It reacts with nucleophilic groups on the enzyme's surface and inhibits its activity by preventing access to substrates.
3,4,5-Trichloropicolinonitrile has been shown to inhibit xanthine oxidase from human erythrocytes and rat liver preparations.
Chemical properties
Technical inquiry about: 3D-PFA48542 3,4,5-Trichloropicolinonitrile
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