Ghrelin (Human, Rat, 1-10)
Ref. 3D-PGH-3627-PI
1mg | 144.00 € | ||
5mg | 357.00 € |
Product Information
- H-Gly-Ser-Ser(n-Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-NH2
Amino acids 1-10 of the peptide hormone Ghrelin which is found in the stomach, brain and other tissues and plays a key role in regulating energy balance. Ghrelin associates with growth hormone secretagogue receptors (GHS-R) through its unique N-octanoyl group which is linked to its serine 3 residue covalently. As a result it is able to influence the body in various ways such as stimulating appetite, nutrient sensing, meal initiation and the regulation of insulin resistance, diabetes and obesity. Its wider functions are also associated with glucose homeostasis, energy homeostasis, cardio-protective effects, bone metabolism and its potential to be a target for cancer means that it can be used to develop therapies for a whole spectrum of diseases. This molecule is used as a research tool for studying cell biology and pharmacology.
Chemical properties
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