Galanin-like Peptide (Human, 1-60)

Ref. 3D-PGL-4391-S

Product Information

• Name: Galanin-like Peptide (Human, 1-60)
• Synonyms: GALP (Human, 1-60),Ala-Pro-Ala-His-Arg-Gly-Arg-Gly-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-His-Leu-Pro-Gln-Met-G ly-Asp-Gln-Asp-Gly-Lys-Arg-Glu-Thr-Ala-Leu-Glu-Ile-Leu-Asp-Leu-Trp-Lys-Ala-Ile-Asp-Gly-Leu-Pro-Tyr-Ser-His-Pro-Pro-Gln-Pro
• Brand: Biosynth
• Description: Galanin-like peptide (GLP-1) is a human peptide that is a potent activator of the GLP-1 receptor. GLP-1 functions as a ligand for the GLP-1 receptor, which is coupled to G proteins. The activation of this receptor leads to increased calcium influx, which in turn triggers the release of insulin from pancreatic beta cells. GLP-1 also inhibits gastric acid secretion and motility, and functions as an inhibitor of glucagon secretion.GLP-1 has been shown to be a potent inhibitor of ion channels. It binds to Kv3 potassium channels and voltage gated sodium channels, inhibiting their activity by binding to their pore region. In addition, GLP-1 inhibits amyloid beta production by inhibiting protein synthesis in rat brain cells.

Chemical properties

• Molecular weight: 6,500.3 g/mol
• Formula: C₂₉₂H₄₅₁N₈₃O₈₄S
• Purity: Min. 95%