![6-Ethynylbenzo[d]thiazole](https://static.cymitquimica.com/products/3D/img/PJB37604.png "Click to enlarge")
Product Information
- Benzothiazole, 6-ethynyl- (9CI)
6-Ethynylbenzo[d]thiazole is an inhibitor of the kinase ALK5, which is a receptor for growth factor-β. This inhibition prevents the phosphorylation of the receptor and subsequent activation of downstream signaling pathways. 6-Ethynylbenzo[d]thiazole also inhibits other kinases such as TGF-β and activin. 6-Ethynylbenzo[d]thiazole has been shown to inhibit cellular proliferation in vitro by inhibiting the activity of enzymes that play a role in cell division. The compound has demonstrated inhibitory activity against a number of cell lines, including human cells and tumor cells derived from human cancer patients.
Chemical properties
Technical inquiry about: 3D-PJB37604 6-Ethynylbenzo[d]thiazole
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