SB-415286

CAS: 264218-23-7

Ref. 3D-PKA21823

Product Information

• Name: SB-415286
• Brand: Biosynth
• Description: SB-415286 is a small molecule inhibitor of GSK-3β. It prevents phosphorylation of the substrate by GSK-3β, thereby preventing the inhibition of downstream signaling pathways, such as those that regulate energy metabolism and neuronal death. SB-415286 has been shown to inhibit 3t3-l1 preadipocytes differentiation into adipocytes, although it does not inhibit proliferation or stimulate apoptosis. This agent also inhibits neuronal death in axons and axon regeneration in t-cell lymphomas, suggesting that this drug may be useful for treating diseases like Alzheimer's disease or stroke.

Chemical properties

• Molecular weight: 359.72 g/mol
• Formula: C₁₆H₁₀ClN₃O₅
• Purity: Min. 95%