Myelin PLP (139-151) acetate

CAS: 122018-58-0

Ref. 3D-PLP-3602-PI

Product Information

• Name: Myelin PLP (139-151) acetate
• Brand: Biosynth
• Description: Myelin PLP (139-151) acetate salt is a cyclic peptide that is derived from the sequence of human myelin basic protein and contains the sequence PLP (139-151). This peptide has shown to have antioxidative properties. It has been shown to have an inhibitory effect on the production of proinflammatory cytokines in experimental autoimmune encephalomyelitis (EAE), which is a model for multiple sclerosis. The peptide has also been shown to block signal pathways, such as toll-like receptor 4, and decrease Ca2+ overload. Clinical relevance remains unclear.

Chemical properties

• Molecular weight: 1,521.76 g/mol
• Formula: C₇₂H₁₀₄N₂₀O₁₇•(C₂H₄O₂)x
• Purity: Min. 95%