Hepcidin (Mouse) (Bulk)

Ref. 3D-PLP-3773-PI

Product Information

• Name: Hepcidin (Mouse) (Bulk)
• Synonyms: Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr, Liver-Expressed Antimicrobial P eptide 1 (Mouse) Hepcidin-25 (murine) Hepcidin-1 (mouse)
• Brand: Biosynth
• Description: Bulk product of the mouse Hepcidin peptide hormone, which displays both iron regulation properties and anti-microbial activity. The disulfide bonds within this product are undetermined and it is available as a Trifluoroacetate Salt. Hepcidin is crucial to iron homeostasis in that it binds to ferroportin and inhibits it post translationally from exporting iron. Additionally Hepcidin is also known as LEAP-1 (liver-expressed antimicrobial peptide) due to it limiting the amount of circulating iron that is available to pathogens when it is induced by inflammatory cytokines. However this reduction in circulating iron lowers the amount needed for erythropoiesis. Thus conditions such as anemia of chronic disease may occur. This product can be used for researching disorders where iron is dysregulated.

Chemical properties

• Molecular weight: 2,754.2 g/mol
• Formula: C₁₁₁H₁₆₉N₃₁O₃₅S₈
• Purity: Min. 95%