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Hepcidin / LEAP-1
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Hepcidin / LEAP-1

CAS: 342790-21-0

Ref. 3D-PLP-4392-S

100µg
447.00 €
Estimated delivery in United States, on Thursday 2 Jan 2025

Product Information

Name:
Hepcidin / LEAP-1
Synonyms:
  • Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys- Cys-Gly-Met-Cys-Cys-Lys-Thr (disulfide bonded) Hepcidin-25 DTHFPICIFCCGCCHRSKCGMCCKT
  • HepcidinHepc25 (human)
  • Hepcidin-25 (human)
  • Hepcidin-25
  • H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-Oh
Description:

A Human liver-expressed peptide hormone involved in the dual activities of being an iron regulator whilst also displaying anti-microbial activity. Hepcidin regulates iron through binding and inhibiting the iron exporter ferroportin. During infection or inflammation Hepcidin is induced, namely by inflammatory cytokines . As a result iron release from macrophages, hepatocytes, and enterocytes is reduced, and the internalization and degradation of ferroportin occurs. Therefore the availability of circulating iron for use by pathogens is decreased. A negative consquence of this however is a condition known as anemia inflammation which is a consquence of less iron being available for erythropoiesis. As it plays a role in many iron disorders it can be used in diagnostic and therapeutic applications. The disulfide bonds of this product have been formed by random oxidation and biological activity can not be guaranteed.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
2,789.4 g/mol
Formula:
C113H170N34O31S9
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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