HLA leader peptide LLL (8mer)
Ref. 3D-PP41942
1mg
210.00€
10mg
243.00€
100mg
428.00€
Product Information
Name:HLA leader peptide LLL (8mer)
Synonyms:
- H-VMAPRTLL-OH
Brand:Biosynth
Description:Fragment of the signal peptide from endogenous HLA Class I molecules which is also found in viral glycoproteins, for example human Cytomegalovirus (hCMV) protein UL40. When presented on a cell surface via HLA-E molecules, the HLA- VMAPRTLLL complex binds NKG2A receptors on Natural Killer (NK) cells and some CD8⁺ cytotoxic T cells to reduce their cytotoxic activity. Blocking this interaction is an attractive opportunity for immune checkpoint (IC) approach therapies. This is relevant in both cancer therapies, and viral infections, where endogenous HLA Class I peptide presentation is exploited to escape immune attack.
In one study, VMAPRTLLL UL4015-23 was found in 10% congenital cytomegalovirus (cCMV) strains.Peptide H-VMAPRTLL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
In one study, VMAPRTLLL UL4015-23 was found in 10% congenital cytomegalovirus (cCMV) strains.Peptide H-VMAPRTLL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Technical inquiry about: HLA leader peptide LLL (8mer)
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.