H-PK-OH

Ref. 3D-PP46059

Product Information

• Name: H-PK-OH
• Synonyms: NH2-Pro-Lys-OH

Description

Peptide H-PK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-PK-OH include the following: Incorporation of 2, 3-diaminopropionic acid into linear cationic amphipathic peptides produces pH-sensitive vectors Y Lan , B Langlet-Bertin, V Abbate , LS Vermeer - , 2010 - Wiley Online Libraryhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201000073 Cell selectivity and mechanism of action of short antimicrobial peptides designed from the cell-penetrating peptide Pep-1 WL Zhu, KS Hahm, SY Shin - of the European Peptide Society, 2009 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/psc.1145 The pH dependence of peptide hydrolysis by nitrocarboxypeptidase A WL Mock, JT Chen - Archives of Biochemistry and Biophysics, 1980 - Elsevierhttps://www.sciencedirect.com/science/article/pii/0003986180902118 pKa values of peptides in aqueous and aqueous-organic media: Prediction of chromatographic and electrophoretic behaviour V Sanz-Nebot, I Toro, F Benavente - Journal of Chromatography , 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S002196730101398X Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologues while sparing paralogous proteases V Baeriswyl, H Rapley, L Pollaro, C Stace - , 2012 - bicycletherapeutics.comhttps://www.bicycletherapeutics.com/wp-content/uploads/2022/06/23_CHEMMEDCCHEM_Bicyclic-peptides-with-optimized-ring-size-inhibit-plasma_01072012-1.pdf Effect of the alpha-amino group on peptide retention behaviour in reversed-phase chromatography Determination of the pKa values of the alpha-amino group of 19 different N TJ Sereda, CT Mant, AM Quinn, RS Hodges - Journal of Chromatography A, 1993 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021967399870034 Cu (II) interaction with N-terminal fragments of human and mouse beta-amyloid peptide T Kowalik-Jankowska, M Ruta-Dolejsz - Journal of inorganic , 2001 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0162013401002264 Selectively 2H-labeledGlu/Asp: application to pKa measurements in Abeta amyloid peptides S Zhang, JP Lee - The Journal of peptide research, 2000 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1034/j.1399-3011.2000.00143.x pK values of the ionizable groups of proteins RL Thurlkill, GR Grimsley , JM Scholtz - Protein science, 2006 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1110/ps.051840806 Chemical models of peptide formation in translation RE Watts, AC Forster - Biochemistry, 2010 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi1000273 Peptide bond characteristics RB Martin - Metal ions in biological systems, 2001 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=n5SFL38rGIsC&oi=fnd&pg=PA1&dq=(%22NH2-Pro-Lys-OH%22+OR+%22PK%22+OR+%22H-PK-OH%22)+AND+peptide&ots=kFb4PUG6dP&sig=DyMWUlzy8LmoCab2BwrGfomxpiY Peptide bond characteristics RB Martin - Metal ions in biological systems, 2001 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=n5SFL38rGIsC&oi=fnd&pg=PA1&dq=(%22NH2-Pro-Lys-OH%22+OR+%22PK%22+OR+%22H-PK-OH%22)+AND+peptide&ots=kFb4PUG78J&sig=oBQ1X2DhcbVgxoe1qmmoAkNDRCY Determination and Modeling of Peptide pKa by Capillary Zone Electrophoresis R Plasson , H Cottet - Analytical chemistry, 2006 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ac060406f Design of specific serine protease inhibitors based on a versatile peptide scaffold: conversion of a urokinase inhibitor to a plasma kallikrein inhibitor P Xu, M Xu, L Jiang , Q Yang, Z Luo - Journal of medicinal , 2015 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.5b01128 The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm O Ovadia, Y Linde, C Haskell-Luevano - Bioorganic & medicinal , 2010 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0968089609010943 Experimental and calculated shift in pKa upon binding of phosphotyrosine peptide to the SH2 domain of p56lck NJ de Mol, MB Gillies , MJE Fischer - Bioorganic & medicinal chemistry, 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0968089601004072 Strategic approaches to optimizing peptide ADME properties L Di - The AAPS journal, 2015 - Springerhttps://link.springer.com/article/10.1208/s12248-014-9687-3 Residue-Specific pKa Measurements of the beta-Peptide and Mechanism of pH-Induced Amyloid Formation K Ma, EL Clancy, Y Zhang , DG Ray - Journal of the , 1999 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja990864o Phosphorylation of peptide substrates for the catalytic subunit of cAMP-dependent protein kinase. JA Adams , SS Taylor - Journal of Biological Chemistry, 1993 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021925818530209 Influence of charge and size of terminal amino-acid residues on local conformational states and shape of alanine-based peptides J Makowska , K Bagià „ska, A Skwierawska - Peptide , 2008 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.21077 Acidic-basic properties of three alanine-based peptides containing acidic and basic side chains: Comparison between theory and experiment J Makowska , K Bagià „ska, A Liwo - Peptide , 2008 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.21046 pH responsive micelle self-assembled from a new amphiphilic peptide as anti-tumor drug carrier J Liang, WL Wu, XD Xu , RX Zhuo, XZ Zhang - Colloids and surfaces B , 2014 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0927776513006772 Sensing pH via p-cyanophenylalanine fluorescence: Application to determine peptide pKa and membrane penetration kinetics IM Pazos , IA Ahmed , MIL Berraca­os, F Gai - Analytical biochemistry, 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0003269715002031 The Effect of a Peptide Helix Macrodipole on the pKa of an Asp Side Chain Carboxylate HV Joshi, MS Meier - Journal of the American Chemical Society, 1996 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja960592e Determination of the membrane translocation pK of the pH-low insertion peptide HL Scott , JM Westerfield , FN Barrera - Biophysical journal, 2017 - cell.comhttps://www.cell.com/biophysj/pdf/S0006-3495(17)30753-1.pdf Potential of collagen-like triple helical peptides as drug carriers: Their in vivo distribution, metabolism, and excretion profiles in rodents H Yasui, CM Yamazaki, H Nose, C Awada - Peptide , 2013 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.22234 A summary of the measured pK values of the ionizable groups in folded proteins GR Grimsley , JM Scholtz , CN Pace - Protein Science, 2009 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/pro.19 Impact of organ impairment on the pharmacokinetics of therapeutic peptides and proteins EP Fletcher, M Sahre, YY Hon, A Balakrishnan - The AAPS Journal, 2023 - Springerhttps://link.springer.com/article/10.1208/s12248-023-00819-0 PK modulation of haptenylated peptides via non-covalent antibody complexation E Hoffmann, A Konkar, S Dziadek, HP Josel - Journal of controlled , 2013 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0168365913003684 Determination of acid dissociation constants of peptide side-chain functional groups by two-dimensional NMR DL Rabenstein, SP Hari, A Kaerner - Analytical chemistry, 1997 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ac970675t Fmoc-Diphenylalanine Self-Assembly Mechanism Induces Apparent pKa Shifts C Tang, AM Smith , RF Collins , RV Ulijn , A Saiani - Langmuir, 2009 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/la900653q [10] Design and use of peptide substrates for protein kinases BE Kemp , RB Pearson - Methods in enzymology, 1991 - Elsevierhttps://www.sciencedirect.com/science/article/pii/007668799100134I In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pK a of the peptide histidine is less than 3.0 BA Katz, RT Cass - Journal of Biological Chemistry, 1997 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)56917-4/abstract Structure-Activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH2 at the human melanocortin-1 and-4 receptors: arginine substitution AWH Cheung, W Danho, J Swistok, L Qi - Bioorganic & medicinal , 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0960894X02004596 Synthesis and evaluation of non-hydrolyzable phospho-lysine peptide mimics A Hauser, E Poulou, F Muller - A European Journal, 2021 - Wiley Online Libraryhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.202003947 peptides. LIII. Synthesis and biological activities of some pseudo-peptide analogs of PKSI-527, a plasma kallikrein selective inhibitor: the importance of the peptide A Fukumizu, Y TSUDA, K Wanaka, M TADA - Chemical and , 1999 - jstage.jst.go.jphttps://www.jstage.jst.go.jp/article/cpb1958/47/8/47_8_1141/_article/-char/ja/

• Brand: Biosynth