PUMA amide peptide

Ref. 3D-PP50268

Product Information

• Name: PUMA amide peptide
• Synonyms: Ac-EQWAREIGAQLRRMADDLNA-NH2
• Brand: Biosynth
• Description: PUMA (p53 upregulated modulator of apoptosis) is a potent pro-apoptotic protein that plays a critical role in stress-induced cell death. It is primarily activated by the tumor suppressor p53 in response to DNA damage, but can also be triggered by other factors in response to various cellular stresses. PUMA functions by disrupting the balance of Bcl-2 family proteins, leading to mitochondrial dysfunction and caspase activation. Due to its involvement in various diseases, PUMA is considered a potential therapeutic target for both cancer and neurodegenerative diseases.