RFRP-1 (Human)

CAS: 311309-25-8

Ref. 3D-PP50946

Product Information

• Name: RFRP-1 (Human)
• Synonyms: RFRP-1 (Human) H-MPHSFANLPLRF-NH2
• Brand: Biosynth
• Description: Neuropeptide:Neuropeptides are small signaling molecules produced and released by neurons engaged in many physiological functions. Indeed, neuropeptides act on neural substrates such as G protein-coupled receptors (GPCRs), tyrosine-kinase receptor, insuline-like peptides and also ion channels. Actions of neuropeptides result in slow-onset, long-lasting modulation of synaptic transmission.Pro-FMRFamide-related neuropeptide VF:Pro-FMRFamide-related neuropeptide VF also called neuropeptide VF precursor are expressed in neurons in mediobasal hypothalamus. Neuropeptide VF precursor is a propeptide which is cleaved in three others peptide: Neuropeptide RFRP-1, RFRP-2 and RFRP-3.Neuropeptide RFRP-1 (81-92):Neuropeptide RFRP-1 play a role in the negative regulation of gonadotropin synthesis and secretion. Neuropeptide RFRP-1 is an agonist of the NPFF1 and NPFF2 receptors. In rats, Neuropeptide RFRP-1 increases prolactin release. Neuropeptide RFRP-1 (81-92) MPHSFANLPLRF-NH2 is a part of Neuropeptide RFRP-1 and is used to study NPFF receptors.

Chemical properties

• Molecular weight: 1,428.73 g/mol
• Formula: C₆₇H₁₀₁N₁₉O₁₄S