Substance P (Human, Bovine, Rat, Mouse)

CAS: 11035-08-8

Ref. 3D-PSP-4014

Product Information

• Name: Substance P (Human, Bovine, Rat, Mouse)
• Synonyms: Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 • 3AcOH • 5H2O
• Brand: Biosynth
• Description: Substance P is a member of the tachykinin neuropeptide family which is produced in the central nervous system (CNS) and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.

Chemical properties

• Molecular weight: 1,617.84 g/mol
• Formula: C₆₃H₉₈N₁₈O₁₃S•3CH₃COOH•5H₂O
• Purity: Min. 95%