[D-Pro2,D-Trp7,9]-Substance P

CAS: 80434-86-2

Ref. 3D-PSP-4113-V

Product Information

• Name: [D-Pro2,D-Trp7,9]-Substance P
• Synonyms: Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH2
• Brand: Biosynth
• Description: This product is a Substance P antagonist and is available as a 0.5mg vial. Substance P is a neuropeptide that is involved in the transmission of pain signals and inflammation. It is a member of the tachykinin neuropeptide family and is produced in the central nervous system and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.

Chemical properties

• Molecular weight: 1,515.8 g/mol
• Formula: C₇₄H₁₀₆N₂₀O₁₃S
• Purity: Min. 95%