[D-Pro2,D-Trp7,9]-Substance P (1ea)

Ref. 3D-PSP-4113

Product Information

• Name: [D-Pro2,D-Trp7,9]-Substance P (1ea)
• Synonyms: Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH2 • 3HCI • 6H2O
• Brand: Biosynth
• Description: This product is a Substance P antagonist and is available in the Hydrochloride salt form. Substance P is a member of the tachykinin neuropeptide family which is produced in the central nervous system (CNS) and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.

Chemical properties

• Molecular weight: 1,733.3 g/mol
• Formula: C₇₄H₁₀₆N₂₀O₁₃S•3HCI•6H₂O
• Purity: Min. 95%