[D-Pro4,Trp7,9]-Substance P (4-11)

Ref. 3D-PSP-4114-V

Product Information

• Name: [D-Pro4,Trp7,9]-Substance P (4-11)
• Synonyms: D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH2
• Brand: Biosynth
• Description: Substance P (4-11) is a peptide that is a member of the tachykinin family. This protein is released by neurons and acts as a neurotransmitter in the brain, where it binds to neurokinin receptors. The structure of Substance P (4-11) has been determined using high-resolution nuclear magnetic resonance spectroscopy and X-ray crystallography. It contains four tryptophans, seven prolines, and nine amino acids in total. Substance P (4-11) has been shown to bind to neurokinin receptors, which are ligand-gated ion channels found on the surface of cells. Binding of this protein leads to an increase in cell permeability through ion channels and causes an increase in intracellular calcium levels.

Chemical properties

• Molecular weight: 1,134.4 g/mol
• Formula: C₅₇H₇₅N₁₃O₁₀S
• Purity: Min. 95%