[Tyr34]-Parathyroid Hormone (Bovine, 1-34 Amide)

Ref. 3D-PTH-4179-V

Product Information

• Name: [Tyr34]-Parathyroid Hormone (Bovine, 1-34 Amide)
• Synonyms: Ala-Val-Ser-Glu-Ile-Gln-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn- Tyr-NH2[Tyr34]-PTH (Bovine, 1-34 Amide)
• Brand: Biosynth
• Description: Amino acids 1-34 of the Pararthyroid Hormone (PTH) containing a tyrosine residue and disulfide bonds between Cys3-Cys14. This product is of Bovine source and available as a 0.5mg vial. Parathyroid hormone (PTH) is a peptide hormone that regulates calcium and phosphate homeostasis. PTH stimulates the production of active vitamin D, which increases calcium absorption from the gut and promotes reabsorption of calcium in the kidney. The inhibitory effect of PTH on renal phosphate excretion causes hyperphosphatemia and hypocalcemia. PTH also stimulates osteoblasts to produce more bone matrix, resulting in increased bone mineralization and density. It is used as a research tool to study protein interactions, activation, ligand binding, receptor regulation and ion channels. It has been shown to have effects on some cell types such as T-cells, B-cells, neutrophils and mast cells. In addition to its effects on bone metabolism, PTH also has many other functions including vasoconstriction, inhibition of food intake and stimulation of glucose production by the liver.

Chemical properties

• Molecular weight: 4,123.7 g/mol
• Formula: C₁₈₃H₂₈₉N₅₅O₅₀S₂
• Purity: Min. 95%