TIP39 (Human, Bovine)

Ref. 3D-PTH-4479-S

Product Information

• Name: TIP39 (Human, Bovine)
• Synonyms: Ser-Leu-Ala-Leu-Ala-Asp-Asp-Ala-Ala-Phe-Arg-Glu-Arg-Ala-Arg-Leu-Leu-Ala-Ala-Leu-Glu-Arg-Arg-His-Trp-Leu-Asn-Ser-Tyr-Met-His-Lys-Leu- Leu-Val-Leu-Asp-Ala-Pro, Tuberoinfundibular Peptide 39, TIP 7-39, TIP 39
• Brand: Biosynth
• Description: TIP39 is a peptide inhibitor that is a member of the TIP family. It inhibits the activity of calcineurin, a calcium-dependent phosphatase enzyme, and thereby prevents it from dephosphorylating nuclear factor of activated T cells cytoplasmic 1 (NFATc1), which regulates signaling pathways that control inflammatory responses. TIP39 has been shown to inhibit calcineurin in both human and bovine cell lines. This drug has been used as a research tool to study peptide-receptor interactions and ion channels.

Chemical properties

• Molecular weight: 4,504.2 g/mol
• Formula: C₂₀₂H₃₂₅N₆₁O₅₄S
• Purity: Min. 95%