Product Information
- (E)-3-Phenyl-N-[2,2,2-trichloro-1-[(4-chlorophenyl)carbamothioylamino]ethyl]prop-2-enamide
Sal-003 is a small molecule that dephosphorylates phosphatases. It has been shown to protect cells from cisplatin-induced nephrotoxicity and growth factor withdrawal in vitro. In vivo, Sal-003 reduced the radiation-induced loss of protein synthesis in wild-type mice and was also found to suppress apoptotic signaling in human breast cancer cells. The protective effects of Sal-003 are thought to be due to its ability to inhibit the activity of phosphatases, which are important for maintaining cellular homeostasis.
Chemical properties
Technical inquiry about: 3D-PWB47053 Sal-003
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