WZ8040
CAS: 1214265-57-2
Ref. 3D-PYB26557
| 1g | To inquire | ||
| 2g | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- 2-Propenamide, N-[3-[[5-chloro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]thio]phenyl]-
- N-[3-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
- N-[3-[[5-Chloro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]thio]phenyl]-2-propenamide
- Wz-8040
- Wz8040
WZ8040 is a factor receptor inhibitor that blocks the epidermal growth factor receptor (EGFR) family of tyrosine kinase receptors. It is an inhibitor of the EGFR family of tyrosine kinases and has been shown to inhibit proliferation in vitro and in vivo. WZ8040 also inhibits the activation of downstream signaling pathways, including ERK, AKT, and STAT3, which regulate cell survival and proliferation. This drug has been shown to be effective against bladder cancer cells with wild-type EGFR but not those that are resistant to quinazoline-based drugs such as PD168393 or pelitinib.
Chemical properties
Technical inquiry about: 3D-PYB26557 WZ8040
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