Dioscin

CAS: 19057-60-4

Ref. 3D-Q-100228

Product Information

• Name: Dioscin
• Synonyms: (3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranoside, (3beta,14xi,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside, (3beta,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside, (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside, 3-O-β-<span class="text-smallcaps">D</smallcap>-α-<smallcap>L</smallcap>-Rhamnopyranosyl(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl(1→2)]-β-<smallcap>D</span>-glucopyranoside-diosgenin, Beta-D-Glucopyranoside,(3-Beta,25R)-Spirost-5-En-3-Ylo-6-Deoxy-Alpha-L-Mannop, Collettiside III, Collettisideiii, Dioscin(P), Dioscine, Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside, Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranoside, Diosgenin bis-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2 and 1→4)-β-<smallcap>D</span>-glucopyranoside, Paris III, Parissaponin III, Polyphyllin III, Yranosyl-(1-2)-O-(6-Deoxy-Alpha-L-Mannopyranosyl)-(1-4))-, β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→4)]-, β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-

Description

Dioscin is a natural product that belongs to the class of flavonoids. It has been shown to significantly inhibit cell proliferation, induce apoptosis, and induce differentiation in 3T3-L1 preadipocytes. Dioscin also inhibits the growth of HL-60 cells by binding to their cell nuclei and reduces the expression of growth factor β1. This compound also exhibits anti-atherosclerotic effects by inhibiting lipid metabolism. Dioscin inhibits the activation of NF-κB, which is a transcription factor that regulates the expression of genes involved in inflammatory cascades and cellular responses to stress. Dioscin also binds to Toll-like receptor (TLR) 4, inducing TLR4 signaling pathways and increasing proinflammatory cytokines such as IL-6 and TNFα.

• Brand: Biosynth

Chemical properties

• Molecular weight: 869.04 g/mol
• Formula: C₄₅H₇₂O₁₆
• Purity: Min. 98.0 Area-%